Isotopically Labeled Compounds
Medchemexpress LLC Deoxycholic acid sodium salt | 302-95-4 | 414.55 | 500 MG
Deoxycholic acid sodium salt is a bile acid, a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptor TGR5. It is for research use only and not sold to patients.
- Activates G protein-coupled bile acid receptor TGR5
- High purity (99.89%)
- White to off-white solid appearance
- Suitable for research in intestinal metabolism and biological activity studies
- Stable at 4°C for solid form, and in solvent at -80°C or -20°C for extended periods
Medchemexpress LLC Caspofungin-d4 (MK-0991-d4; L-743872-d4) | 1131958-73-0 | 1097.34 | 500 UG
Caspofungin-d4 (MK-0991-d4; L-743872-d4) is a deuterium labeled Caspofungin, a potent antifungal agent that inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan. This compound is valuable for research, particularly in understanding pharmacokinetic and metabolic profiles through deuteration.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated for quantitation during drug development.
Medchemexpress LLC GlcCer (d18:1/18:0) | 95119-86-1 | 99.93% | 728.09 | 5 MG
GlcCer (d18:1/18:0) (C18 Glucosyl (β) ceramide (d18:1/18:0)) is a glycosphingolipid. It is promising for research of Parkinson disease and dementia with Lewy bodies.
- A glycosphingolipid
- Promising for research of Parkinson disease and dementia with Lewy bodies
- Powder: -20°C for 3 years
- In solvent: -80°C for 6 months, -20°C for 1 month
Cayman Chemical PalmItIc AcId-d2 500mg
An internal standard for the quantification of palmitic acid by GC- or LC-MS
Medchemexpress LLC HY-15777AS 5mg , Ribociclib-d6 (hydrochloride) CAS: Purity:>98%
HY-15777AS 5mg Ribociclib-d6 (hydrochloride) CAS: Ribociclib D6 (LEE011 D6) hydrochloride is a deuterium labeled Ribociclib. Ribociclib is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Prostaglandin D2-d4 | 211105-29-2 | 98.8% | 356.49 | C20H28D4O5 | 50 UG
Prostaglandin D2-d4 is a deuterium-labeled analogue of prostaglandin D2 supplied as a solution in methyl acetate for use as an internal standard in GC- or LC-MS assays. It is intended for research use to support accurate quantification of PGD2 in biological samples and analytical workflows.
- Deuterium-labeled internal standard for PGD2 quantification by GC- or LC-MS.
- High chemical purity (98.8%) for reliable analytical performance.
- Supplied as a microgram-scale solution suitable for trace-level analyses.
- Stable when stored at -20°C for up to two years.
- Molecular formula C20H28D4O5 and molecular weight 356.49 aid compound identification.
Medchemexpress LLC Bromocyclohexane-d11 | 35558-49-7 | MFCD00190385 | >98.0% | 174.12 | C6D11Br | 100 MG
Bromocyclohexane-d11 is the deuterium-labeled analogue of bromocyclohexane provided for research use as a stable isotope reagent and internal standard. It is intended for mechanistic studies, tracer experiments, and mass spectrometry applications where deuterium labeling improves compound tracking and quantitation. Not for human or clinical use.
- Deuterium-labeled tracer for mechanistic studies.
- Suitable as an internal standard for GC-MS quantitation.
- High isotopic enrichment (>98 atom % D) for reliable detection.
- Available in mg-scale packages for analytical workflows.
- For research use only; not for patient or clinical use.
Medchemexpress LLC Camptothecin-d5 | 1329616-37-6 | 99.6% | 353.38 | 1 MG
Camptothecin-d5 is the deuterium labeled Camptothecin. Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM. Camptothecin (CPT) exhibits powerful antineoplastic activity against colorectal, breast, lung and ovarian cancers, modulates hypoxia-inducible factor-1α (HIF-1α) activity by changing microRNAs (miRNA) expression patterns in human cancer cells.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC L-Tryptophan-α,β,β,2,4,5,6,7-d8 | 1233395-93-1 | 212.27 | 100 MG
L-Tryptophan-d8 is the deuterium-labeled L-Tryptophan. L-Tryptophan is an essential amino acid and a precursor of serotonin, melatonin, and vitamin B3.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
- Deuteration has potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Cetirizine-d8 | 774596-22-4 | 96.5% | 396.94 | 5 MG
Cetirizine-d8 is a deuterium labeled Cetirizine. Cetirizine is a second-generation antihistamine and the carboxylated metabolite of hydroxyzine. It is a specific, orally active, and long-acting histamine H1-receptor antagonist. Cetirizine exhibits antiallergic properties and inhibits eosinophil chemotaxis during the allergic response.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Isotope-labeled compounds
- Internal standard for clinical mass spectrometry
- Isotope-labeled inhibitors
- Isotope-labeled metabolites
- Deuterium (2H, D) stable isotope-labeled inhibitors
- Stable isotope-labeled inhibitors for use in in vivo cell experiments
- Therapeutic drug monitoring: TDM
Medchemexpress LLC Zanubrutinib-d5 | 00-00-0 | 99.0% | 476.58 | C27H24D5N5O3 | 5 MG
Zanubrutinib-d5 is a deuterium-labeled isotopologue of zanubrutinib supplied as a research-grade reference standard for analytical, pharmacokinetic, and mechanistic studies. The compound incorporates five deuterium atoms (C27H24D5N5O3) and is provided as a high-purity powder suitable for LC-MS and tracer experiments.
- Deuterium-labeled isotopologue for tracer and quantification studies.
- Suitable for LC-MS internal standard and pharmacokinetic assays.
- High purity for improved analytical accuracy.
- Stable powder formulation with specified storage conditions.
- Available in small mg pack sizes for method development and validation.
Medchemexpress LLC 1-hydroxypyrene-d9 | 132603-37-3 | MFCD04972163 | 100.0% | 227.31 | C16HD9O | 1 MG
1-Hydroxypyrene-d9 is the deuterium-labeled analogue of 1-hydroxypyrene supplied as a reference standard for analytical and biomonitoring applications. It is used as an internal standard for LC-MS/MS quantitation to assess exposure to polycyclic aromatic hydrocarbons and to improve accuracy and recovery correction in environmental and toxicology analyses.
- Deuterium-labeled internal standard for mass spectrometry.
- High purity for reliable quantitation.
- Solid material, white to off-white, suitable for analytical workflows.
- Intended for biomonitoring of PAH exposure in urine and environmental samples.
- Available in small sizes optimized for analytical use.
Sigma Aldrich Fine Chemicals Biosciences D-Glucose 6-phosphate sodium salt | 54010-71-8 | MFCD00006611 | 500 mg
D-Glucose 6-phosphate sodium salt | Purity: ≥98% | Mol Wt: 282.12 | 54010-71-8 | MFCD00006611 | 500 mg
Medchemexpress LLC Cinnamic acid-13C3 (3-phenylacrylic acid-13C3) | 2734410-01-4 | 151.14 | 5 MG
Cinnamic acid-13C3 (3-Phenylacrylic acid-13C3) is the 13C labeled Cinnamic acid. Cinnamic acid has potential use in cancer intervention, with IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC D-Erythrose-4-13C 5mg | 90913-08-9 | 121.10 g/mol | C3(13C)H8O4 | 5 MG
D-Erythrose-4-13C is the 13C-labeled form of D-erythrose supplied as a solution in water for research use. It serves as a tracer and internal standard for quantitative analysis by NMR, GC-MS, and LC-MS.
- 13C-labeled D-erythrose for tracer and quantitation
- Supplied as a solution in water at a defined concentration (0.107 M for listed sizes)
- Available in small, pre-measured sizes suitable for analytical workflows (5 mg, 10 mg, 25 mg)
- Molecular formula C3(13C)H8O4; molecular weight 121.10 g/mol
- Intended for research use only